2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B0319
    Tioconazole
    		Inhibitor 99.90%
    Tioconazole (UK-20349) is a broad-spectrum antifungal imidazole derivative. Tioconazole inhibits several dermatophytes and yeasts, with MIC50 values of less than 3.12 mg/L and 9 mg/L, respectively. Additionally, Tioconazole exhibits anti-parasitic activity. Tioconazole exerts anticancer activity by inhibiting the PI3K/AKT/mTOR signaling pathway and blocking autophagy. Tioconazole is applicable for research in the fields of anti-infection and anticancer therapy.
    Tioconazole
  • HY-B0817
    Pyridaben
    		Inhibitor 99.27%
    Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC50 value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria). Pyridaben also significantly inhibits rat mitochondrial mtNOS function.
    Pyridaben
  • HY-118448
    2,4-Diacetylphloroglucinol
    		Inhibitor 99.27%
    2,4-Diacetylphloroglucinol is a polyketide antibiotic produced by Pseudomonas fluorescens. 2,4-Diacetylphloroglucinol exhibits broad-spectrum toxicity against various organisms such as bacteria, fungi, oomycetes, and nematodes. 2,4-Diacetylphloroglucinol can also inhibit plant pathogens and affect the root development of tomato seedlings.
    2,4-Diacetylphloroglucinol
  • HY-116564
    Lotilaner
    		Inhibitor 99.84%
    Lotilaner is a parasiticide, acts as a potent non-competitive antagonist of insects GABACl receptors, with an IC50 of 23.84 nM for Drosophila melanogaster GABA receptor. No effect on a dog GABAA receptor.
    Lotilaner
  • HY-N0336
    3-Butylidenephthalide
    		Inhibitor
    3-Butylidenephthalide (Butylidenephthalide) is a phthalic anhydride derivative identified in Ligusticum chuanxiong Hort, and has larvicidal activity (LC50 of 1.56 mg/g for Spodoptera litura larvae).
    3-Butylidenephthalide
  • HY-B1761
    Santonin
    		Inhibitor 99.73%
    Santonin is an active principle of the plant Artemisia cina, which is formely used to treat worms.
    Santonin
  • HY-B2031
    Pyriproxyfen
    		Inhibitor 99.00%
    Pyriproxyfen is a juvenile hormone analog, preventing larvae from developing into adulthood and thus rendering them unable to reproduce.
    Pyriproxyfen
  • HY-W016586
    Acivicin
    		Inhibitor 99.52%
    Acivicin (AT-125), a natural product produced by Streptomyces sviceus is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin can across the blood-brain barrier and has anti-cancer, anti-parasitic properties.
    Acivicin
  • HY-B0935
    Benzyl benzoate
    		Inhibitor 99.94%
    Benzyl benzoate (Phenylmethyl benzoate) is an orally active anti-scabies agent, acaricide (EC50= 0.06 g/m2) and fungicide. Benzyl benzoate is an angiotensin II (Ang II) inhibitor with antihypertensive effects. Benzyl benzoate can be used in perfumes, pharmaceuticals and the food industry.
    Benzyl benzoate
  • HY-10411
    AZ960
    		Inhibitor
    AZ960 is a potent and specific inhibitor of the JAK2 kinase with a Ki of 0.45 nM.
    AZ960
  • HY-12643
    Eprinomectin
    		Inhibitor 98.02%
    Eprinomectin (MK-397) is a type of avermectin. Eprinomectin, as a broad-spectrum fungicide, has insecticidal, insecticidal and acaricidal activities. Eprinomectin induces apoptosis and autophagy in prostate cancer cells and has antitumor activity.
    Eprinomectin
  • HY-B1400
    Diiodohydroxyquinoline
    		Inhibitor 98.0%
    Diiodohydroxyquinoline (Iodoquinol, 5,7-Diiodo-8-hydroxyquinoline, 5,7-Diiodo-8-quinolinol) has an orally active and satisfactory antiparasitic properties. Diiodohydroxyquinoline exhibits mutagenic potential in mice and potent anti-SARS-CoV-2 activity with an EC50 value of 1.38 μM in VeroE6 cells. Diiodohydroxyquinoline's antimutagen is ascorbic acid. Diiodohydroxyquinoline is promising for research in inflammationin, testinal amebiasis, amebic liver abscess and chronic nonspecific diarrheas.
    Diiodohydroxyquinoline
  • HY-N6950
    Hederacolchiside A1
    		Inhibitor 99.0%
    Hederacolchiside A1, isolated from Pulsatilla chinensis, suppresses proliferation of tumor cells by inducing apoptosis through modulating PI3K/Akt/mTOR signaling pathway. Hederacolchiside A1 has antischistosomal activity, affecting parasite viability both in vivo and in vitro.
    Hederacolchiside A1
  • HY-B1548
    Benznidazole
    		Inhibitor 99.90%
    Benznidazole (Ro 07-1051) is an antiparasitic medication, with an IC50 of 20.35 μM for Colombian T. cruzi strains, and has been used in the treatment of Chagas disease.
    Benznidazole
  • HY-14430
    Cipargamin
    		Inhibitor 99.90%
    Cipargamin (NITD609) is an potent antimalarial compound, with an IC50 of appr 1 nM against P. falciparum.
    Cipargamin
  • HY-W012732
    Isoquinoline
    		Inhibitor 99.58%
    Isoquinoline is an analog of pyridine. Isoquinoline-based alkaloids, such as p-tolyl bisisoquinoline, phthaloyl isoquinoline, and naphthyl isoquinoline, exhibit anticancer activity. Berberine, an isoquinoline alkaloid, exerts anti-inflammatory effects in diabetic mice by downregulating the gene expression ratios of pro-/anti-inflammatory and Th1/Th2 cytokines. Additionally, some isoquinoline-based compounds also possess antidepressant, antibacterial, antimalarial, and anti-HIV activities.
    Isoquinoline
  • HY-128204
    AN3661
    		Inhibitor 99.89%
    AN3661, a potent antimalarial lead compound, targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue subunit 3 (PfCPSF3). AN3661 inhibits Plasmodium falciparum laboratory-adapted strains (mean IC50=32 nM), Ugandan field isolates (mean ex vivo IC50=64 nM), and murine P. berghei and P. falciparum infections.
    AN3661
  • HY-B0751
    Fumagillin
    		Inhibitor ≥99.0%
    Fumagillin(NSC9168) is an antimicrobial compound first isolated in 1949 from the fungus Aspergillus fumigatu. Fumagillin can inhibits HIV‐1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity.
    Fumagillin
  • HY-N2392
    Kukoamine A
    		Inhibitor 99.88%
    Kukoamine A is a natural occurring spermine derivative, acts as a potent inhibitor of trypanothione reductase (Ki, 1.8 μM), with antihypertensive activity.
    Kukoamine A
  • HY-12784A
    Cycloguanil hydrochloride
    		Inhibitor 99.93%
    Cycloguanil hydrochloride, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes.
    Cycloguanil hydrochloride
Parasite Isoform Comparison

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